Tomei had won the previous year for Best Breakthrough Performance for My Cousin Vinny.
The following year, Tomei appeared alongside Downey again in the romantic comedy Only You.
She also made an appearance on The Simpsons as movie star Sara Sloane, who falls in love with Ned Flanders.
The role earned her rave reviews and the Theatre World Award for outstanding debut on stage. Pesci and trying to look small, or arguing about a leaky faucet in terms that demonstrate her knowledge of plumbing.
She then appeared in Nick Cassavetes's Unhook the Stars.